Ferrous fumarate also known as Iron (II) fumarate is a reddish orange powder with the chemical formula C4H2FeO4. Ferrous fumarate is manufactured from fumaric acid in the presence of ammonia and ferrous sulfate. The manufacturing processes are regulated by regulatory bodies such as U.S. Pharmacopeial Convention (USP) and EU-Pharmacopeia (Ph.Eur.). Ferrous fumarate is a high iron-containing compound, while the pure form of ferrous fumarate sample contains more than 30% of iron. The commonly prescribed dose of ferrous fumarate is a 300 milligram tablet which roughly contains 98 milligram of iron. Owing to its high iron contents, it is capable of meeting with the demand for iron of all organisms owing to which it is used as an iron supplement. Ferrous fumarate is a non toxic, tasteless and odorless compound. The marketed variety of ferrous fumarate does not contain any animal or cell culture-derived products and additives. Ferrous fumarate is extensively used in the pharmaceutical industry. Hemoglobin is an important constituent of human blood and iron is an important constituent of hemoglobin. Hence iron is vital for the production of red blood cells in our body and helps hemoglobin to carry oxygen to various parts of the body. Lack of iron in our body will lead to oxygen deficiency and in turn lead to tiredness and fatigue. Ferrous fumarate tables are used to satisfy iron requirements in case of deficiency. Ferrous fumarate tables are prescribed in case of anemia and during pregnancy. Ferrous fumarate, ferrous gluconate and ferrous sulfate fall under the category of oral iron supplements. Ferrous fumarate is more commonly used among the three because it does not have any potential side effects. Usage of ferrous fumarate additives are also recommended for baby food. FDA and European Medicines Agency are the two major government agencies regulating the usage of ferrous fumarate in the pharmaceutical products.
The market for ferrous fumarate is growing substantially owing to the fast growing pharmaceutical industry. Global pharmaceutical industry, the major end user of ferrous fumarate, is worth more than US$ 900 Bn. North America is the largest market for ferrous fumarate because of the well organized pharmaceutical market and presence of international drug manufacturers such as Pfizer and Johnson & Johnsons. U.S. accounts for the largest market for ferrous fumarate in the world. Asia Pacific is the fastest growing market. Increasing number of manufacturing activites in Asia Pacific is driving the pharmaceutical industry. Emerging countries in Asia Pacific especially India and China are the largest consumers of ferrous fumarate. The pharmaceutical industry in India is developing considerably due to which India is one of the largest exporters of ferrous fumarate. Despite the economic slowdown in Europe the demand for ferrous fumarate is increasing. The enhancing demand for ferrous fumarate in Europe is primarily because of the presence of significant pharmaceutical product manufacturing nations such as Belgium, Germany, and Italy. The demand for ferrous fumarate is comparatively low in Rest of the World due to the absence of pharmaceutical product manufactures. Demand for this product is anticipated to increase owing to the development of pharmaceutical manufacturing industry especially in Russia, which accounts as the seventh largest manufacturer of pharmaceutical products and has significant share in the ferrous fumarate market.
Some of the manufacturers of ferrous fumarate are Vifom Pharma, Ironwood Pharmaceuticals, Galenica group, Allied Biochem Pvt. Ltd., Lonye Technology Limited, Shreeji Industries and Henan Sinotech Import & Export Corporation.
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