Market Research Reports

Computational Biology Market (Pharmacodynamics, Cellular Modeling, Computational Genomics, Proteomics, Pharmacogenomics, Pharmacokinetics, Human Simulation Software, Drug Discovery & Development) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2012 - 2018

112pages
Published Date: 2013-05-07
 

Description



The computational biology market is predicted to have a notable growth owing to its wide use by biotechnology and pharmaceutical companies to reduce the incidences of late stage failures of their drugs and thereby curb R&D expenditure. This market involves application of biology and information technology field for drug discovery and drug development. Computational biology also assists in reducing extensive use of human in clinical trials and is therefore useful for pediatric trials, trials on pregnant women and orphan disease research. The computational biology market has witnessed significant growth in the past due to rise in late stage drug failure coupled with its ability to reduce extensive use of humans in clinical trials. 

This report provides an in-depth and comprehensive analysis of the computational biology market on the basis of application, tools and by services. This report studies the global market for computational biology through the perspective of cellular modeling and disease modeling. In application segment, the report covers cellular & biological simulation and disease modeling and simulation application or CADD (Computer Aided Drug Design). Cellular & biological simulation market has also been segmented on the basis of computational genomics, computational proteomics, pharmacogenomics and others (transcriptomics/ metabolomics). Disease modeling and simulation segment is categorized into drug discovery and drug development. The market of drug discovery is divided into target identification, target validation, lead discovery and lead optimization. Drug development market is segmented as preclinical, clinical trials and human body simulation software. The market of clinical trials is studies based on phase I, phase II and phase III trials. 

The market of computational biology market, by tools is categorized into database, IT infrastructure (hardware) and analysis software and services types. The computational biology services market highlights the trend of in-house computational biology and external or contract computational biology. The report also provides various types of technological advancements taking place in each segment. All the above mentioned segments are analyzed on the basis of market size in terms of USD million and their forecasts for the period 2012 to 2018 have also been provided. The CAGR (%) for each market segment has been estimated for the forecast period 2012 to 2018, considering 2011 as the base year. In addition, this report covers participation of different organizations of the U.S. and the U.K. for the development of computational biology market.
 
The market is also forecasted in terms of value (USD million) for the period 2012 – 2018 for four major geographic regions, namely North America, Europe, Asia-Pacific and Rest of the World (RoW). Market sizes, forecasts and % CAGR for each region have been provided in geography segment. A detailed qualitative analysis of the factors responsible for driving and restraining the growth of the computational biology market and future opportunities are covered in the report. Moreover, a PESTLE analysis has been done while estimating individual geographies in order to provide current as well as future status. A list of recommendations for existing as well as new entrants has been discussed in the study. This recommendation chapter provides assistance to industry players on ways to enter this market or to establish sustainable competitive advantage.

Some of the key market players of the global computational biology market include Genedata AG, Nimbus Discovery LLC, Rhenovia Pharma SAS, Certara, Chemical Computing Group, Inc., Compugen, Ltd,  Simulation Plus, Inc., Schrodinger, Leadscope, Inc., Accelrys, Entelos and Insilico Biotechnology AG. Market players are profiled in this report on the basis of attributes such as company overview, financial overview, business strategies adopted by the companies to ensure sustainability and maximize profits, product portfolio and recent developments. The competitive landscape of this industry has been covered under market share analysis by key players.

Table of Contents


Table of Content

Chapter 1 Introduction
1.1 Report Description
1.2 Market Segmentation
1.3 Scope Of The Report
1.4 Research Methodology
      1.4.1 Sources
               1.4.1.1 Secondary Research
               1.4.1.2 Primary Research
               1.4.1.3 Models
1.5 Assumptions

Chapter 2 Executive Summary
2.1 Market Snapshot: Global Computational Biology Market (2011 & 2018)
2.2 Global Computational Biology Market, by Types, 2011 (USD Million)

Chapter 3 Global Computational Biology Market Dynamics
3.1 Market Overview
3.2 Drivers
      3.2.1 Failure Of Drug Candidates in Late Stage of Clinical Trials
               3.2.1.1 Average Cost to Develop One New Drug (1975 -2011) (USD Million)
               3.2.1.2 Trend of Rise in Failure of Phase II Clinical Trials (2006- 2012)
               3.2.1.3 Reasons For Failure (%) in Phase II & Phase III
      3.2.2 Enhanced Computational Tools
      3.2.3 Improved Government Funding &Industrial Support
3.3 Restraints
      3.3.1 Lack of Standardization
      3.3.2 Non-Verified Predictive Models
3.4 Challenges
      3.4.1 Shortage of Skilled Resources
      3.4.2 Data Storage
3.5 Opportunities
      3.5.1 Cloud Computing
      3.5.2 Modelling And Simulations in Paediatrics Drug Development
3.6 Porters Five Forces Analysis
      3.6.1 Bargaining Power of Suppliers
      3.6.2 Bargaining Power of Buyers
      3.6.3 Threat of New Entrants
      3.6.4 Threat Of Substitutes
      3.6.5 Competitive Rivalry
3.7 Market Attractiveness Analysis
      3.7.1 Market Attractiveness Analysis: Global Computational Biology Market, by Geography
3.8 End User Analysis
      3.8.1 End User Analysis: Global Computational Biology Market, 2011 & 2018 (%)

Chapter 4 Global Computational Biology Market, by Applications
4.1 Introduction
      4.1.1 Cellular Modelling and Simulation
               4.1.1.1 Computational Genomics
                          4.1.1.1.1 Global Computational Genomics Market Revenues, 2010 – 2018 (USD Million)
               4.1.1.2 Computational Proteomics
                          4.1.1.2.1 Global Computational Proteomics Market Revenues, 2010 – 2018 (USD Million)
               4.1.1.3 Pharmacogenomics
                          4.1.1.3.1 Global Computational Pharmacogenomics Market Revenues, 2010 – 2018 (USD Million)
               4.1.1.4 Others (Metabolomics/ Transcriptomics)
                          4.1.1.4.1 Global Computational Others (Metabolomics/Transcriptomics) Market Revenue, 2010 – 2018 (USD Million)
      4.1.2 Disease Modelling And Simulation Applications / CADD (Computer Aided Drug Design)
              4.1.2.1 Drug Discovery
                         4.1.2.1.1 Global Computational Drug Discovery Market Revenues, 2010 – 2018 (USD Million)
                         4.1.2.1.2 Target Identification
                                       4.1.2.1.2.1 Global Computational Target Identification Market Revenues, 2010 – 2018 (USD Million)
                         4.1.2.1.3 Target Validation
                                       4.1.2.1.3.1 Global Computational Target Validation Market Revenues, 2010 – 2018 (USD Million)
                         4.1.2.1.4 Lead Identification/Discovery
                                       4.1.2.1.4.1 Global Computational Lead Identification Market Revenues, 2010 – 2018 (USD Million)
                         4.1.2.1.5 Lead Optimization
                                       4.1.2.1.5.1 Global Computational Lead Optimization Market Revenues, 2010 – 2018 (USD Million)
             4.1.2.1 Drug Development
                         4.1.2.1.1 Preclinical
                                       4.1.2.1.1.1 Global Computational Preclinical Trials Market Revenues, 2010 – 2018 (USD Million)
                         4.1.2.1.2 Clinical Trials
                                       4.1.2.1.2.1 Global Computational Clinical Trials Market Revenues, 2010 – 2018 (USD Million)
                                       4.1.2.1.2.2 Phase I
                                       4.1.2.1.2.3 Global Computational Clinical Trials Phase I Market Revenues, 2010 – 2018 (USD Million)
                                       4.1.2.1.2.4 Phase II
                                       4.1.2.1.2.5 Global Computational Clinical Trials Phase II Market Revenues, 2010 – 2018 (USD Million)
                                       4.1.2.1.2.6 Phase III
                                       4.1.2.1.2.7 Global Computational Clinical Trials Phase III Market Revenues, 2010 – 2018 (USD Million)
                         4.1.2.1.3 Human Body Simulation Software
                                       4.1.2.1.3.1 Global Computational Human Simulation Software Market Revenues, 2010 – 2018 (USD Million)

Chapter 5 Global Computational Biology Market, by Tools
5.1 Overview
5.2 Database
      5.2.1 Global Computational Biology Database Market Revenues, 2010 – 2018 (USD Million)
5.3 IT Infrastructure (Hardware)
      5.3.1 Global Computational Biology Hardware Market Revenues, 2010 – 2018 (USD Million)
5.4 Analysis Software & Services
      5.4.1 Global Computational Biology Software Market Revenues, 2010 – 2018 (USD Million)

Chapter 6 Global Computational Biology Market, by Services
6.1 Overview
6.2 In-House Computational Biology
      6.2.1 Global In-House Computational Biology Market Revenues, 2010 – 2018 (USD Million)
6.3 External/Contract Computational Biology
      6.3.1 Global Contract Computational Biology Market Revenues, 2010 – 2018 (USD Million)

Chapter 7 Global Computational Biology Market, by Geography
7.1 Overview
7.2 North America
      7.2.1 North America Computational Biology Market Revenues, 2010 – 2018 (USD Million)
7.3 Europe
      7.3.1 Europe Computational Biology Market Revenues, 2010 – 2018 (USD Million)
7.4 Asia
      7.4.1 Asia Computational Biology Market Revenues, 2010 – 2018 (USD Million)
7.5 ROW
      7.5.1 Row Computational Biology Market Revenues, 2010 – 2018 (USD Million)

Chapter 8 Market Share Analysis
8.1 Market Share by Key Players
      8.1.1 Global Computational Biology Market Share Analysis of Key Players, 2011 (%)

Chapter 9 Recommendations
9.1 Success Strategies
      9.1.1 Rigorous Research and Development (R&D) Initiatives
      9.1.2 Investing in Emerging Economies
      9.1.3 Investing in High-End Technologies
      9.1.4 Collaborations, Mergers and Acquisitions
9.2 Barriers to be Considered
      9.2.1 High Cost of Investment

Chapter 10 Company Profiles
10.1 Accelrys
      10.1.1 Company Overview
      10.1.2 Financial Overview
      10.1.3 Product Portfolio And Services
      10.1.4 Business Strategy
      10.1.5 Recent Developments
10.2 Certara
      10.2.1 Company Profile
      10.2.2 Financial Overview
      10.2.3 Product Portfolio And Services
      10.2.4 Business Strategy
      10.2.5 Recent Developments
10.3 Chemical Computing Group Inc.
      10.3.1 Company Profile
      10.3.2 Financial Overview
      10.3.3 Product Portfolio
      10.3.4 Business Strategy
      10.3.5 Recent Developments
10.4 Compugen, Ltd
      10.4.1 Company Profile
      10.4.2 Financial Overview
      10.4.3 Business Strategy
      10.4.4 Recent Developments
10.5 Entelos
      10.5.1 Company Profile
      10.5.2 Financial Overview
      10.5.3 Product Portfolio And Services
      10.5.4 Business Strategy
      10.5.5 Recent Developments
10.6 Genedata AG
      10.6.1 Company Profile
      10.6.2 Financial Overview
      10.6.3 Product Portfolio And Services
      10.6.4 Business Strategy
      10.6.5 Recent Developments
10.7 Insilico Biotechnology AG
      10.7.1 Company Profile
      10.7.2 Financial Overview
      10.7.3 Product Portfolio
      10.7.4 Business Strategy
      10.7.5 Recent Developments
10.8 Leadscope, Inc
      10.8.1 Company Profile
      10.8.2 Financial  Overview
      10.8.3 Product Portfolio
      10.8.4 Business Strategy
      10.8.5 Recent Developments
10.9 Nimbus Discovery LLC
      10.9.1 Company Profile
      10.9.2 Financial Overview
      10.9.3 Product Portfolio
      10.9.4 Business Strategy
      10.9.5 Recent Developments
10.10 Rhenovia  Pharma SAS
      10.10.1 Company Profile
      10.10.2 Financial Overview
      10.10.3 Product Portfolio And Services
      10.10.4 Business Startegy
      10.10.5 Recent Developments
10.11 Schrodinger
      10.11.1 Company Overview
      10.11.2 Financial Overview
      10.11.3 Product Portfolio And Services
      10.11.4 Business Strategy
      10.11.5 Recent Developments
10.12 Simulation Plus, Inc.
      10.12.1 Company Profile
      10.12.2 Financial Overview
      10.12.3 Product Portfolio And Services
      10.12.4 Business Strategy
      10.12.5 Recent Developments

List of Figures

FIG. 1 Global Computational Biology: Market Segmentation
FIG. 2 Global Computational Biology Market, By Types, 2011 (USD Million)
FIG. 3 Average Cost to Develop one New Drug (1975 -2011) (USD Million)
FIG. 4 Trend of Rise in Failure of Phase II Clinical Trials (2006- 2012)
FIG. 5 Reasons for Failure (%) in Phase II & Phase III
FIG. 6 Porter’s Five Forces Analysis for Computational Biology Market
FIG. 7 Market Attractiveness Analysis: Global Computational Biology Market, By Geography
FIG. 8 End User Analysis: Global Computational Biology Market, 2011 & 2018 (%)
FIG. 9 Global Computational Genomics Market Revenues, 2010 – 2018 (USD Million)
FIG. 10 Global Computational Proteomics Market Revenues, 2010 – 2018 (USD Million)
FIG. 11 Global Computational Pharmacogenomics Market Revenues, 2010 – 2018 (USD Million)
FIG. 12 Global Computational Others (Metabolomics/ Transcriptomics) Market Revenue, 2010 – 2018 (USD Million)
FIG. 13 Global Computational Drug Discovery Market Revenues, 2010 – 2018 (USD Million)
FIG. 14 Global Computational Target Identification Market Revenues, 2010 – 2018 (USD Million)
FIG. 15 Global Computational Target Validation Market Revenues, 2010 – 2018 (USD Million)
FIG. 16 Global Computational Lead Identification Market Revenues, 2010 – 2018 (USD Million)
FIG. 17 Global Computational Lead Optimization Market Revenues, 2010 – 2018 (USD Million)
FIG. 18 Global Computational Preclinical Trials Market Revenues, 2010 – 2018 (USD Million)
FIG. 19 Global Computational Clinical Trials Market Revenues, 2010 – 2018 (USD Million)
FIG. 20 Global Computational Clinical Trials Phase I Market Revenues, 2010 – 2018 (USD Million)
FIG. 21 Global Computational Clinical Trials Phase II Market Revenues, 2010 – 2018 (USD Million)
FIG. 22 Global Computational Clinical Trials Phase III Market Revenues, 2010 – 2018 (USD Million)
FIG. 23 Global Computational Human Simulation Software Market Revenues, 2010 – 2012 (USD Million)
FIG. 24 Global Computational Biology Database Market Revenues, 2010 – 2018 (USD Million)
FIG. 25 Global Computational Biology Hardware Market Revenues, 2010 – 2018 (USD Million)
FIG. 26 Global Computational Biology Software Market Revenues, 2010 – 2018 (USD Million)
FIG. 27 Global In-House Computational Biology Market Revenues, 2010 – 2018 (USD Million)
FIG. 28 Global Contract Computational Biology Market Revenues, 2010 – 2018 (USD Million)
FIG. 29 North America Computational Biology Market Revenues, 2010 – 2018 (USD Million)
FIG. 30 Europe Computational Biology Market Revenues, 2010 – 2018 (USD Million)
FIG. 31 Asia Computational Biology Market Revenue, 2010 – 2018 (USD Million)
FIG. 32 Row Computational Biology Market Revenues, 2010 – 2018 (USD Million)
FIG. 33 Global Computational Biology Market Share Analysis Of Key Players, 2011 (%)
FIG. 34 Annual Revenues: Accelrys, 2009 - 2011 (USD Million)
FIG. 35 Annual Revenue: Compugen, 2010 – 2012 (USD Million)
FIG. 36 Annual Revenues: Simulation Plus, Inc., 2010 – 2012 (USD Million)

List of Tables

TABLE 1 Global Computational Biology Market: Snapshot (2011 & 2018)
TABLE 2 R&D Function by Expenditure (%)
TABLE 3 Global Computational Biology Market Revenues, by Segments, 2010 – 2018 (USD Million)
TABLE 4 Global Cellular Modeling and Biology Simulation Market Revenues, by Types, 2010 – 2018 (USD Million)
TABLE 5 Global Cellular Modeling and Biology Simulation Market Revenues, by Geography, 2010 – 2018 (USD Million)
TABLE 6 Global Disease Modeling and Simulation Market Revenues, by Types, 2010 - 2018 (USD Million)
TABLE 7 Global Disease Modeling and Simulation Market Revenues, by Geography, 2010 - 2018 (USD Million)
TABLE 8 Global Computational Drug Development Market Revenues, by Types, 2010 - 2018 (USD Million)
TABLE 9 Software Packages for PBPK Modeling
TABLE 10 Global Computational Biology Market Revenues, by Tools, 2010- 2018 (USD Million)
TABLE 11 Global Computational Services Market Revenues, by Services, 2010- 2018 (USD Million)
TABLE 12 Global Computational Biology Market, by Geography, 2010- 2018 (USD Million)

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Free Market Analysis


The computational biology market deals with the use of biology and computers for drug discovery and drug development. This is conducted through modeling and simulation models for pharmacokinetics and pharmacodynamics. Rise in late stage drug failure coupled with contraction of innovative drugs has led to huge financial losses to the biotech pharmaceutical companies. It has therefore become imperative for pharmaceutical companies to invest in computational biology. In 2011, the global computational biology market was valued to be USD 760.2 million and is expected to grow at a CAGR of 21.3% from 2012 to 2018. 

Computational biology also helps to reduce extensive use of humans in trials and is therefore useful for pediatric trials, trials on pregnant women and orphan disease research. The drug discovery market accounts to be the largest market for computational biology as its use at this stage helps in reduction of drug failure in the subsequent phase i.e. development phase. Currently, there is a large market of contract service providers of computational biology; nonetheless multinational pharmaceutical companies are setting up their own computational biology centers to fasten the process of drug discovery and development. Governments across the globe are funding infrastructure and academic courses to improve and increase the number of computational biologists. 

Large pharmaceutical companies such as Pfizer, Roche, Novartis, and Sanofi are now exploring this market to have better outcomes of clinical trials. The drugs which have failed in the last stage of clinical trials are also being studied using computational biology to understand and apply its use for other disease indications. Though North America remains the largest market in the world, Asian countries namely India and China are witnessing fast growth and are predicted to emerge as dominating markets in the near future. The major players of this market are Schrödinger, Accelrys, Compugen, Entelos, Rhenovia Pharma and others.

global-computational-biology-market-revenues-by-segments-2010-2018
 

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