Computational Biology Market

Computational Biology Market (Pharmacodynamics, Cellular Modeling, Computational Genomics, Proteomics, Pharmacogenomics, Pharmacokinetics, Human Simulation Software, Drug Discovery & Development) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2012 - 2018

Global Computational Biology Market: Snapshot

The skyrocketing rates of drugs along with the continuously rising rate of failure of drugs in the late stage of clinical trials are prompting pharma players to shift their focus from traditional methods of clinical trials to predictive models. The increasing demand for predictive models is, therefore, providing a significant boost to the growth of the global computational biology market. Moreover, the increasing funding from governments and private organizations for research and development in this field is propelling the market.

On the other hand, the lack of standardization and dearth of skilled labor is limiting the market from realizing its utmost potential. However, the emergence of cloud computing is likely to shape future of the market. The opportunity in the global computational biology market was worth US$1.64 bn in 2015 and is estimated to rise to US$2.93 bn by the end of 2018, progressing at a phenomenal CAGR of 21.3% from 2012 to 2018.

In-house to Remain Most Valuable Service Segment through 2018

Based on tools, database was the leading segment in terms of revenue in 2015. Their demand is likely to remain strong in the forthcoming years owing to the fact that they serve as the ground for modeling and simulation. However, the analysis software and services segment is expected to outperform database by the end of forecast period. The increasing need for cost-effective software that ensures simplified modeling and simulation is contributing to the growth of the segment. The segment is estimated to rise at a noteworthy CAGR of 25.0% during the forecast period.

On the basis of services, the in-house segment will account for the lion’s share throughout the forecast period, expanding at a 22.6% CAGR during the same period. Current trends in the global market indicate that multinational biotech pharma companies are shifting their own research and development setups in countries with cheap manpower cost such as India, China, and Brazil. This coupled with tax benefits offered by the governments of these nations is anticipated to reduce the cost of conducting in-house research. These factors are, therefore, driving the growth of the segment.

North America to Retain Dominance as Government Organizations Encourage Research and Development Activities

North America will be the frontrunner in the market in terms of revenue throughout the forecast period, with the U.S. being the leading revenue contributor. The growth of the region is supplemented by the conducive environment for the development of bioinformatics and computational biology created by government organizations and continual research and development efforts by pharmaceutical giants. In addition, the U.S. federal government is encouraging the growth of the market through provision of funds for research and development and academic centers using modeling and simulation for drug discovery.

The market for computational biology in Asia Pacific is largely centered in countries such as India, China, and Japan. The presence of a large and trained talent pool of researchers and engineers coupled with robust computational infrastructure is assisting the region in treading along a healthy growth track. Favorable government initiatives and increasing collaborations among international biologists, bioinformatics, and local scientists are augmenting the growth of the region. Owing to these factor, the region is poised to progress at a CAGR of 27.5% during the same period. Some of the prominent players in the global computational biology market are Accelrys, Certara, Chemical Computing Group Inc., Compugen, Entelos, Ltd, Genedata AG, and Insilico Biotechnology AG.

    Table of Content
     
    Chapter 1 Introduction
    1.1 Report Description
    1.2 Market Segmentation
    1.3 Scope Of The Report
    1.4 Research Methodology
          1.4.1 Sources
                   1.4.1.1 Secondary Research
                   1.4.1.2 Primary Research
                   1.4.1.3 Models
    1.5 Assumptions
     
    Chapter 2 Executive Summary
    2.1 Market Snapshot: Global Computational Biology Market (2011 & 2018)
    2.2 Global Computational Biology Market, by Types, 2011 (USD Million)
     
    Chapter 3 Global Computational Biology Market Dynamics
    3.1 Market Overview
    3.2 Drivers
          3.2.1 Failure Of Drug Candidates in Late Stage of Clinical Trials
                   3.2.1.1 Average Cost to Develop One New Drug (1975 -2011) (USD Million)
                   3.2.1.2 Trend of Rise in Failure of Phase II Clinical Trials (2006- 2012)
                   3.2.1.3 Reasons For Failure (%) in Phase II & Phase III
          3.2.2 Enhanced Computational Tools
          3.2.3 Improved Government Funding &Industrial Support
    3.3 Restraints
          3.3.1 Lack of Standardization
          3.3.2 Non-Verified Predictive Models
    3.4 Challenges
          3.4.1 Shortage of Skilled Resources
          3.4.2 Data Storage
    3.5 Opportunities
          3.5.1 Cloud Computing
          3.5.2 Modelling And Simulations in Paediatrics Drug Development
    3.6 Porters Five Forces Analysis
          3.6.1 Bargaining Power of Suppliers
          3.6.2 Bargaining Power of Buyers
          3.6.3 Threat of New Entrants
          3.6.4 Threat Of Substitutes
          3.6.5 Competitive Rivalry
    3.7 Market Attractiveness Analysis
          3.7.1 Market Attractiveness Analysis: Global Computational Biology Market, by Geography
    3.8 End User Analysis
          3.8.1 End User Analysis: Global Computational Biology Market, 2011 & 2018 (%)
     
    Chapter 4 Global Computational Biology Market, by Applications
    4.1 Introduction
          4.1.1 Cellular Modelling and Simulation
                   4.1.1.1 Computational Genomics
                              4.1.1.1.1 Global Computational Genomics Market Revenues, 2010 – 2018 (USD Million)
                   4.1.1.2 Computational Proteomics
                              4.1.1.2.1 Global Computational Proteomics Market Revenues, 2010 – 2018 (USD Million)
                   4.1.1.3 Pharmacogenomics
                              4.1.1.3.1 Global Computational Pharmacogenomics Market Revenues, 2010 – 2018 (USD Million)
                   4.1.1.4 Others (Metabolomics/ Transcriptomics)
                              4.1.1.4.1 Global Computational Others (Metabolomics/Transcriptomics) Market Revenue, 2010 – 2018 (USD Million)
          4.1.2 Disease Modelling And Simulation Applications / CADD (Computer Aided Drug Design)
                  4.1.2.1 Drug Discovery
                             4.1.2.1.1 Global Computational Drug Discovery Market Revenues, 2010 – 2018 (USD Million)
                             4.1.2.1.2 Target Identification
                                           4.1.2.1.2.1 Global Computational Target Identification Market Revenues, 2010 – 2018 (USD Million)
                             4.1.2.1.3 Target Validation
                                           4.1.2.1.3.1 Global Computational Target Validation Market Revenues, 2010 – 2018 (USD Million)
                             4.1.2.1.4 Lead Identification/Discovery
                                           4.1.2.1.4.1 Global Computational Lead Identification Market Revenues, 2010 – 2018 (USD Million)
                             4.1.2.1.5 Lead Optimization
                                           4.1.2.1.5.1 Global Computational Lead Optimization Market Revenues, 2010 – 2018 (USD Million)
                 4.1.2.1 Drug Development
                             4.1.2.1.1 Preclinical
                                           4.1.2.1.1.1 Global Computational Preclinical Trials Market Revenues, 2010 – 2018 (USD Million)
                             4.1.2.1.2 Clinical Trials
                                           4.1.2.1.2.1 Global Computational Clinical Trials Market Revenues, 2010 – 2018 (USD Million)
                                           4.1.2.1.2.2 Phase I
                                           4.1.2.1.2.3 Global Computational Clinical Trials Phase I Market Revenues, 2010 – 2018 (USD Million)
                                           4.1.2.1.2.4 Phase II
                                           4.1.2.1.2.5 Global Computational Clinical Trials Phase II Market Revenues, 2010 – 2018 (USD Million)
                                           4.1.2.1.2.6 Phase III
                                           4.1.2.1.2.7 Global Computational Clinical Trials Phase III Market Revenues, 2010 – 2018 (USD Million)
                             4.1.2.1.3 Human Body Simulation Software
                                           4.1.2.1.3.1 Global Computational Human Simulation Software Market Revenues, 2010 – 2018 (USD Million)
     
    Chapter 5 Global Computational Biology Market, by Tools
    5.1 Overview
    5.2 Database
          5.2.1 Global Computational Biology Database Market Revenues, 2010 – 2018 (USD Million)
    5.3 IT Infrastructure (Hardware)
          5.3.1 Global Computational Biology Hardware Market Revenues, 2010 – 2018 (USD Million)
    5.4 Analysis Software & Services
          5.4.1 Global Computational Biology Software Market Revenues, 2010 – 2018 (USD Million)
     
    Chapter 6 Global Computational Biology Market, by Services
    6.1 Overview
    6.2 In-House Computational Biology
          6.2.1 Global In-House Computational Biology Market Revenues, 2010 – 2018 (USD Million)
    6.3 External/Contract Computational Biology
          6.3.1 Global Contract Computational Biology Market Revenues, 2010 – 2018 (USD Million)
     
    Chapter 7 Global Computational Biology Market, by Geography
    7.1 Overview
    7.2 North America
          7.2.1 North America Computational Biology Market Revenues, 2010 – 2018 (USD Million)
    7.3 Europe
          7.3.1 Europe Computational Biology Market Revenues, 2010 – 2018 (USD Million)
    7.4 Asia
          7.4.1 Asia Computational Biology Market Revenues, 2010 – 2018 (USD Million)
    7.5 ROW
          7.5.1 Row Computational Biology Market Revenues, 2010 – 2018 (USD Million)
     
    Chapter 8 Market Share Analysis
    8.1 Market Share by Key Players
          8.1.1 Global Computational Biology Market Share Analysis of Key Players, 2011 (%)
     
    Chapter 9 Recommendations
    9.1 Success Strategies
          9.1.1 Rigorous Research and Development (R&D) Initiatives
          9.1.2 Investing in Emerging Economies
          9.1.3 Investing in High-End Technologies
          9.1.4 Collaborations, Mergers and Acquisitions
    9.2 Barriers to be Considered
          9.2.1 High Cost of Investment
     
    Chapter 10 Company Profiles
    10.1 Accelrys
          10.1.1 Company Overview
          10.1.2 Financial Overview
          10.1.3 Product Portfolio And Services
          10.1.4 Business Strategy
          10.1.5 Recent Developments
    10.2 Certara
          10.2.1 Company Profile
          10.2.2 Financial Overview
          10.2.3 Product Portfolio And Services
          10.2.4 Business Strategy
          10.2.5 Recent Developments
    10.3 Chemical Computing Group Inc.
          10.3.1 Company Profile
          10.3.2 Financial Overview
          10.3.3 Product Portfolio
          10.3.4 Business Strategy
          10.3.5 Recent Developments
    10.4 Compugen, Ltd
          10.4.1 Company Profile
          10.4.2 Financial Overview
          10.4.3 Business Strategy
          10.4.4 Recent Developments
    10.5 Entelos
          10.5.1 Company Profile
          10.5.2 Financial Overview
          10.5.3 Product Portfolio And Services
          10.5.4 Business Strategy
          10.5.5 Recent Developments
    10.6 Genedata AG
          10.6.1 Company Profile
          10.6.2 Financial Overview
          10.6.3 Product Portfolio And Services
          10.6.4 Business Strategy
          10.6.5 Recent Developments
    10.7 Insilico Biotechnology AG
          10.7.1 Company Profile
          10.7.2 Financial Overview
          10.7.3 Product Portfolio
          10.7.4 Business Strategy
          10.7.5 Recent Developments
    10.8 Leadscope, Inc
          10.8.1 Company Profile
          10.8.2 Financial  Overview
          10.8.3 Product Portfolio
          10.8.4 Business Strategy
          10.8.5 Recent Developments
    10.9 Nimbus Discovery LLC
          10.9.1 Company Profile
          10.9.2 Financial Overview
          10.9.3 Product Portfolio
          10.9.4 Business Strategy
          10.9.5 Recent Developments
    10.10 Rhenovia  Pharma SAS
          10.10.1 Company Profile
          10.10.2 Financial Overview
          10.10.3 Product Portfolio And Services
          10.10.4 Business Startegy
          10.10.5 Recent Developments
    10.11 Schrodinger
          10.11.1 Company Overview
          10.11.2 Financial Overview
          10.11.3 Product Portfolio And Services
          10.11.4 Business Strategy
          10.11.5 Recent Developments
    10.12 Simulation Plus, Inc.
          10.12.1 Company Profile
          10.12.2 Financial Overview
          10.12.3 Product Portfolio And Services
          10.12.4 Business Strategy
          10.12.5 Recent Developments
    List of Tables
     
    TABLE 1 Global Computational Biology Market: Snapshot (2011 & 2018)
    TABLE 2 R&D Function by Expenditure (%)
    TABLE 3 Global Computational Biology Market Revenues, by Segments, 2010 – 2018 (USD Million)
    TABLE 4 Global Cellular Modeling and Biology Simulation Market Revenues, by Types, 2010 – 2018 (USD Million)
    TABLE 5 Global Cellular Modeling and Biology Simulation Market Revenues, by Geography, 2010 – 2018 (USD Million)
    TABLE 6 Global Disease Modeling and Simulation Market Revenues, by Types, 2010 - 2018 (USD Million)
    TABLE 7 Global Disease Modeling and Simulation Market Revenues, by Geography, 2010 - 2018 (USD Million)
    TABLE 8 Global Computational Drug Development Market Revenues, by Types, 2010 - 2018 (USD Million)
    TABLE 9 Software Packages for PBPK Modeling
    TABLE 10 Global Computational Biology Market Revenues, by Tools, 2010- 2018 (USD Million)
    TABLE 11 Global Computational Services Market Revenues, by Services, 2010- 2018 (USD Million)
    TABLE 12 Global Computational Biology Market, by Geography, 2010- 2018 (USD Million)

    List of Figures

     

    FIG. 1 Global Computational Biology: Market Segmentation

    FIG. 2 Global Computational Biology Market, By Types, 2011 (USD Million)

    FIG. 3 Average Cost to Develop one New Drug (1975 -2011) (USD Million)

    FIG. 4 Trend of Rise in Failure of Phase II Clinical Trials (2006- 2012)

    FIG. 5 Reasons for Failure (%) in Phase II & Phase III

    FIG. 6 Porter’s Five Forces Analysis for Computational Biology Market

    FIG. 7 Market Attractiveness Analysis: Global Computational Biology Market, By Geography

    FIG. 8 End User Analysis: Global Computational Biology Market, 2011 & 2018 (%)

    FIG. 9 Global Computational Genomics Market Revenues, 2010 – 2018 (USD Million)

    FIG. 10 Global Computational Proteomics Market Revenues, 2010 – 2018 (USD Million)

    FIG. 11 Global Computational Pharmacogenomics Market Revenues, 2010 – 2018 (USD Million)

    FIG. 12 Global Computational Others (Metabolomics/ Transcriptomics) Market Revenue, 2010 – 2018 (USD Million)

    FIG. 13 Global Computational Drug Discovery Market Revenues, 2010 – 2018 (USD Million)

    FIG. 14 Global Computational Target Identification Market Revenues, 2010 – 2018 (USD Million)

    FIG. 15 Global Computational Target Validation Market Revenues, 2010 – 2018 (USD Million)

    FIG. 16 Global Computational Lead Identification Market Revenues, 2010 – 2018 (USD Million)

    FIG. 17 Global Computational Lead Optimization Market Revenues, 2010 – 2018 (USD Million)

    FIG. 18 Global Computational Preclinical Trials Market Revenues, 2010 – 2018 (USD Million)

    FIG. 19 Global Computational Clinical Trials Market Revenues, 2010 – 2018 (USD Million)

    FIG. 20 Global Computational Clinical Trials Phase I Market Revenues, 2010 – 2018 (USD Million)

    FIG. 21 Global Computational Clinical Trials Phase II Market Revenues, 2010 – 2018 (USD Million)

    FIG. 22 Global Computational Clinical Trials Phase III Market Revenues, 2010 – 2018 (USD Million)

    FIG. 23 Global Computational Human Simulation Software Market Revenues, 2010 – 2012 (USD Million)

    FIG. 24 Global Computational Biology Database Market Revenues, 2010 – 2018 (USD Million)

    FIG. 25 Global Computational Biology Hardware Market Revenues, 2010 – 2018 (USD Million)

    FIG. 26 Global Computational Biology Software Market Revenues, 2010 – 2018 (USD Million)

    FIG. 27 Global In-House Computational Biology Market Revenues, 2010 – 2018 (USD Million)

    FIG. 28 Global Contract Computational Biology Market Revenues, 2010 – 2018 (USD Million)

    FIG. 29 North America Computational Biology Market Revenues, 2010 – 2018 (USD Million)

    FIG. 30 Europe Computational Biology Market Revenues, 2010 – 2018 (USD Million)

    FIG. 31 Asia Computational Biology Market Revenue, 2010 – 2018 (USD Million)

    FIG. 32 Row Computational Biology Market Revenues, 2010 – 2018 (USD Million)

    FIG. 33 Global Computational Biology Market Share Analysis Of Key Players, 2011 (%)

    FIG. 34 Annual Revenues: Accelrys, 2009 - 2011 (USD Million)

    FIG. 35 Annual Revenue: Compugen, 2010 – 2012 (USD Million)

    FIG. 36 Annual Revenues: Simulation Plus, Inc., 2010 – 2012 (USD Million)

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