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Collagenase Clostridium Histolyticum Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2015 - 2023

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Collagenase clostridium histolyticum is a type of enzyme formed by the bacterium clostridium histolyticum that helps in the breakdown of collagen. It is majorly used in the treatment of Dupuytren\'s contracture, a medical condition where the fingers of the patient bend towards the palm due to the formation of knots under the skin. The collagenase clostridium histolyticum market is expected witnessed a remarkable growth due to the high prevalence of Dupuytren\'s contracture across the major geographies of the world. Moreover, increasing applicability of collagenase clostridium histolyticum in other medical indications such as wound care and Peyronie\'s disease market will drive the growth of the market in the near future.


Some of the major medications based on collagenase clostridium histolyticum are as follows:

  • XIAFLEX (U.S.)
  • Xiapex (Europe)
  • Collagenase SANTYL

Some of the side-effects often experienced by individuals after receiving collagenase are as follows:

  • Blisters at the injection site
  • Itching of the treated hand
  • Painful erection
  • Painful sexual activity
  • Swollen and painful glands in the underarm or elbow area

In terms of geographical analysis, North America followed by Europe account for the largest market share of collagenase clostridium histolyticum due to the high prevalence Dupuytren’s disease and Peyronie\'s disease in the U.S. Since, the major application of collagenase clostridium histolyticum lies in Dupuytren’s disease, occurrence of this disease is the key factor behind the growth of this market. According to various scientific studies, the prevalence of Dupuytren’s disease in the U.S. is around 4%; moreover, this disease is most often diagnosed in Caucasians of Northern European origin. However, the prevalence of Dupuytren’s disease is sporadic in regions such as Asia and Africa. Hence, the market for collagenase clostridium histolyticum is expected to prosper more in developed regions such as North America and Europe as compared to other regions such as Asia and Africa.


The global collagenase clostridium histolyticum market is witnessing an admirable growth due to the growing prevalence of Dupuytren\'s contracture and Peyronie\'s disease, increasing usage of collagenase in various medical areas such as wound care, pain management, etc. Furthermore, increasing usage of collagenase based products in the burn management and necrotic tissue management are expected to boost the growth of overall collagenase clostridium histolyticum market in the near future. Moreover, due to the lack of other standard medicines and therapies for treating Dupuytren\'s contracture and Peyronie\'s disease, this market is expected to grow at an appreciable pace. Additionally, increasing number of clinical studies focused on finding other applications of collagenase in human healthcare are expected to amplify the growth of collagenase clostridium histolyticum market in developed nations. However, stringent regulatory approval policies of collagenase and high pricing are few of the important factors that might act as hindrances for the growth of this market.


The global collagenase clostridium histolyticum market is highly competitive and consolidated due to the participation and presence of a few major players in this market. The market is expected to witness a steady growth rate due to the increasing prevalence of Dupuytren’s disease and Peyronie\'s disease in developed nations such as the U.S, the U.K. and Spain. Some of the major companies involved in the manufacturing and commercialization of collagenase clostridium histolyticum are Auxilium Pharmaceuticals, Inc., BioSpecifics Technologies Corp., Smith & Nephew plc and Swedish Orphan Biovitrum AB (publ), amongst others.


This research report analyzes this market on the basis of its market segments, major geographies, and current market trends. Geographies analyzed under this research report include 

  • North America 
  • Asia Pacific 
  • Europe
  • Rest of the World  

This report provides comprehensive analysis of 

  • Market growth drivers 
  • Factors limiting market growth
  • Current market trends 
  • Market structure
  • Market projections for upcoming years 

This report is a complete study of current trends in the market, industry growth drivers, and restraints. It provides market projections for the coming years. It includes analysis of recent developments in technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also includes a review of micro and macro factors essential for the existing market players and new entrants along with detailed value chain analysis. 


Reasons for Buying this Report

  • This report provides pin-point analysis for changing competitive dynamics
  • It provides a forward looking perspective on different factors driving or restraining market growth 
  • It provides a six-year forecast assessed on the basis of how the market is predicted to grow 
  • It helps in understanding the key product segments and their future
  • It provides pin point analysis of changing competition dynamics and keeps you ahead of competitors
  • It helps in making informed business decisions by having complete insights of market and by making in-depth analysis of market segments 
  • It provides distinctive graphics and exemplified SWOT analysis of major market segments 

Note : All statements of fact, opinion, or analysis expressed in reports are those of the respective analysts. They do not necessarily reflect formal positions or views of Transparency Market Research.

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