Market Research Reports

Transfection Technology Market (Reagent-based method, Instrument-based method and Virus-based method) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 - 2019

120pages
Published Date: 2014-04-24
 

Description


Transfection is a technique used to introduce nucleic acids (either DNA or RNA) into cells. This technology helps the cells to regulate gene therapy, mutation of cancer cells and protein metabolism by affecting the nuclear genes. The report explains various advancements taking place in this market and analyzes the global transfection technology market by types of methods and applications as well as geographic regions. This report comprises an elaborate executive summary, which includes market snapshot that provides overall information of various segments and sub-segments that are contained in the report. Moreover, executive summary comprises waterfall diagram which is drawn on the basis of most desirable segment of the market. Comparative analysis has also been included in the executive summary that resembles percentage market share of each region (North America, Europe, Asia-Pacific, RoW) in 2012 and 2019 respectively. 

The global market for transfection technology is segmented based on methods as reagent-based method, instrument-based method and virus-based method. The reagent-based method is further segmented as lipid mediated transfection (Lipofection), calcium phosphate, catonic polymers, DEAE-dextran, activated dendrimers and magnetic beads. Likewise, instrument-based method includes electroporation, biolistic technology, microinjection and laserfection. The market for these methods has been extensively analyzed based on consistency, effectiveness and sales revenue of the product developed by the manufacturers. The market size and forecast in terms of USD million for each method type has been provided for the period 2011 to 2019. The report on the transfection technology market also provides % compounded annual growth rate (CAGR) for each market segment for the forecast period 2013 to 2019, considering 2012 as the base year. 

In addition, the global market for transfection technology is segmented based on application into biomedical research, therapeutic delivery (biotherapeutics and electro-chemotherapy and electro-immunotherapy) and protein production. Further the biomedical research segment includes transgenic models, cancer research, gene and protein expression studies and cell-based microarrays for drug discovery and development. The market for these applications of transfection technology has been extensively analyzed based on sales revenue of the required technologies and their geographic distribution. The market size and forecast in terms of USD million for each application has been provided for the period 2011 to 2019. The report on the transfection technology market also provides % compounded annual growth rate (CAGR) for each market segment for the forecast period 2013 to 2019, considering 2012 as the base year.

Geographically, the transfection technology market has been categorized into four major regions: North America, Europe, Asia-Pacific, and Rest of the World (ROW). The market size and forecast for each of these regions have been provided for the period 2011 to 2019 along with CAGR (%) for the forecast period 2013 to 2019. The research study also incorporates competitive scenario of major players in these regions. A detailed qualitative analysis of the factors responsible for driving and restraining the growth of the transfection technology market and future opportunities has been provided in the market overview section. This section of the report also provides market attractiveness analysis and Porter’s five forces analysis and key players’ market share analysis in 2012 in the transfection technology market. 

Market size estimations involved in-depth study of demand of transfection technology products in hospitals, clinics and research organizations and average price range of each segment. Additionally, disease prevalence, geographic presence and historical year-on-year growth has been taken into consideration for calculating the market size. The market size estimated for each category is based on secondary data obtained for all the above factors cumulatively. The data obtained from secondary research was analyzed extensively and has been validated with the help of industry experts in order to arrive at the most accurate market size estimations. Additionally, we have applied top down approach to estimate the global market figure and assumed percentage split to calculate the market by method and application. The entire transfection technology market has been validated thorough extensive secondary and primary research. 

A list of recommendations has been provided for new entrants to help establish a strong presence and for existing market players to increase market share. The report also profiles major players in the transfection technology market based on various attributes such as company overview, financial overview, business strategies, product portfolio and recent developments. Major market players profiled in this report includes Sigma Aldrich Corporation, SignaGen Laboratories, Lonza Group Ltd., Life Technologies, Bio-Rad Laboratories Inc., Promega Corporation and QIAGEN. 

The transfection technology market is segmented into the following categories:
  • Transfection technology market, by Methods
    • Reagent Based Method
      • Lipid mediated transfection (Lipofection)
      • Calcium phosphate
      • Catonic polymers
      • DEAE-dextran
      • Activated dendrimers
      • Magnetic beads
    • Instrument Based Method
      • Electroporation
      • Biolistic technology
      • Microinjection
      • Laserfection
    • Virus Based Method
  • Transfection Technology Market, by Applications
    • Bio-medical Research
      • Transgenic models
      • Cancer Research
      • Gene and protein expression studies
      • Cell based microarrays for drug discovery and development
    • Therapeutic Delivery
      • Biotherapeutics
      • Electro-chemotherapy and electro-immunotherapy
    • Protein Production
  • Transfection Technology Market, by Geography
    • North America
    • Europe
    • Asia-Pacific
    • Rest of The World

Table of Contents


Table of Content

Chapter 1 Preface 
1.1 Report Description 
1.2 Market Segmentation 
1.3 Research Methodology 
1.4 List of Abbreviations

Chapter 2 Executive Summary 
2.1 Market Snapshot: Global Transfection Technology  Market (2012 & 2019) 
      2.1.1 Global Transfection Technology Market, by Methods, 2012 (USD Million) 
2.2 Comparative Analysis: Global Transfection Technology Market, By Geography, 2012 and 2019 (Value %)

Chapter 3 Market Overview 
3.1 Market Definition and Overview 
3.2 Market Dynamics 
      3.2.1 Drivers 
               3.2.1.1 Protein production promotes the use of transfection technology methods 
               3.2.1.2 Emerging biopharmaceutical markets in Asia boost transfection needs 
      3.2.2 Restraints 
               3.2.2.1 High cost prevents sufficient market expansion 
      3.2.3 Opportunities 
               3.2.3.1 Transfection technologies for stem cell research 
3.3 Porters Five Force Analysis for the Global Transfection Technology Market 
      3.3.1 Bargaining Power of Suppliers 
      3.3.2 Bargaining Power of Buyers 
      3.3.3 Threat of Substitutes 
      3.3.4 Threat of New Entrants 
      3.3.5 Competitive Rivalry 
3.4 Market Attractiveness Analysis 
3.5 Competitive Landscape 
      3.5.1 Market Share Analysis by Key Players, 2012 (Value %)

Chapter 4 Global Transfection Technology Market, by Methods 
4.1 Overview 
      4.1.1 Global Transfection Technology Market Revenue, by Methods, 2011 – 2019 (USD Million) 
4.2 Reagent-based Methods 
      4.2.1 Global Reagent Based Market Revenue, by Types, 2011 – 2019 (USD Million) 
      4.2.2 Lipid Mediated Transfection (Lipofection) 
               4.2.2.1 Global Lipid Mediated Transfection Market Revenue, 2011 – 2019 (USD Million) 
      4.2.3 Calcium Phosphate 
               4.2.3.1 Global Calcium Phosphate Transfection Market Revenue, 2011 – 2019 (USD Million) 
      4.2.4 Cationic Polymers 
               4.2.4.1 Global Cationic Polymer Market Revenue, 2011 – 2019 (USD Million) 
      4.2.5 DEAE dextran 
               4.2.5.1 Global DEAE-dextran Market Revenue, 2011 – 2019 (USD Million) 
      4.2.6 Activated Dendrimers 
               4.2.6.1 Global Activated Dendrimers Market Revenue, 2011 – 2019 (USD Million) 
      4.2.7 Magnetic Beads (Magnet-mediated transfection) 
               4.2.7.1 Global Magnetic Beads Transfection Market Revenue, 2011 – 2019 (USD Million) 
4.3 Instrument-based Methods 
      4.3.1 Global Instrument Based Method Revenue, by Types, 2011 – 2019 (USD Million) 
      4.3.2 Electroporation 
               4.3.2.1 Global Electroporation Market Revenue, 2011 – 2019 (USD Million) 
      4.3.3 Biolistic Technology 
               4.3.3.1 Global Biolistic Technology Market Revenue, 2011 – 2019 (USD Million) 
      4.3.4 Microinjection 
               4.3.4.1 Global Microinjection Market Revenue, 2011 – 2019 (USD Million) 
      4.3.5 Laserfection 
               4.3.5.1 Global Biolistic Technology Market Revenue, 2011 – 2019 (USD Million) 
4.4 Virus-based Methods 
      4.4.1 Global Virus Based Method Market Revenue, 2011 – 2019 (USD Million)

Chapter 5 Global Transfection Technology Market, By Application 
5.1 Overview 
      5.1.1 Global Transfection Technology Market Revenue, by Applications, 2011 – 2019 (USD Million) 
5.2 Bio-medical Research 
      5.2.1 Global Bio-medical Research Market Revenue, by Types, 2011 – 2019 (USD Million) 
      5.2.2 Transgenic Models 
               5.2.2.1 Global Transgenic Model Market Revenue, 2011 – 2019 (USD Million) 
      5.2.3 Cancer Research 
               5.2.3.1 Global Cancer Research Market Revenue, 2011 – 2019 (USD Million) 
      5.2.4 Gene and Protein Expression Studies 
               5.2.4.1 Global Gene and Protein Expression Studies Market Revenue, 2011 – 2019 (USD Million) 
      5.2.5 Cell Based Microarray for Drug Discovery and Development 
               5.2.5.1 Global Cell Based Microarray for Drug Discovery and Development Market Revenue, 2011 – 2019 (USD Million) 
5.3 Therapeutic Delivery 
      5.3.1 Global Therapeutics Delivery Market Revenue, by Types, 2011 – 2019 (USD Million) 
      5.3.2 Biotherapeutics 
               5.3.2.1 Global Biotherapeutics Market Revenue, 2011 – 2019 (USD Million) 
      5.3.3 Electro-chemotherapy and Electro-immunotherapy 
               5.3.3.1 Global Electro-chemotherapy and Electro-immunotherapy Market Revenue, 2011 – 2019 (USD Million) 
5.4 Protein Production 
      5.4.1 Global Protein Production Market Revenue, 2011 – 2019 (USD Million)

Chapter 6 Global Transfection Technology Market, by Geography 
6.1 Overview 
      6.1.1 Global Transfection Technology Market Revenue, by Geography, 2011 – 2019 (USD Million) 
6.2 North America 
      6.2.1 North America Transfection Technology Market Revenue, 2011 – 2019 (USD Million) 
6.3 Europe 
      6.3.1 Europe Transfection Technology Market Revenue, 2011 – 2019 (USD Million) 
6.4 Asia-Pacific 
      6.4.1 Asia-Pacific Transfection Technology Market Revenue, 2011 – 2019 (USD Million) 
6.5 Rest of the World (RoW) 
      6.5.1 RoW Transfection Technology Market Revenue, 2011 – 2019 (USD Million)

Chapter 7 Recommendations 
7.1 Market Strategy for Success 
      7.1.1 Develop new technologies and product improvement 
      7.1.2 Enhance product portfolio for stem cell research transfection 
7.2 Barriers and Future Assumptions 
      7.2.1 High cost is a barrier for sufficient market expansion

Chapter 8 Company Profiles 
8.1 Bio-Rad Laboratories, Inc. 
      8.1.1 Company Overview 
      8.1.2 Financial Overview 
      8.1.3 Product Portfolio 
      8.1.4 Business Strategies 
      8.1.5 Recent Developments 
8.2 Harvard Bioscience, Inc. 
      8.2.1 Company Overview 
      8.2.2 Financial Overview 
      8.2.3 Product Portfolio 
      8.2.4 Business Strategies 
      8.2.5 Recent Developments 
8.3 Life Technologies Corporation 
      8.3.1 Company Overview 
      8.3.2 Financial Overview 
      8.3.3 Product Portfolio 
      8.3.4 Business Strategies 
      8.3.5 Recent Developments 
8.4 Lonza Group Ltd. 
      8.4.1 Company Overview 
      8.4.2 Financial Overview 
      8.4.3 Product Portfolio 
      8.4.4 Business Strategies 
      8.4.5 Recent Developments 
8.5 Merck KGaA 
      8.5.1 Company Overview 
      8.5.2 Financial Overview 
      8.5.3 Product Portfolio 
      8.5.4 Business Strategies 
      8.5.5 Recent Developments 
8.6 Mirus Bio LLC 
      8.6.1 Company Overview 
      8.6.2 Financial Overview 
      8.6.3 Product Portfolio 
      8.6.4 Business Strategies 
      8.6.5 Recent Development 
8.7 Polyplus-transfection S.A. 
      8.7.1 Company Overview 
      8.7.2 Financial Overview 
      8.7.3 Product Portfolio 
      8.7.4 Business Strategies 
      8.7.5 Recent Developments 
8.8 Promega Corporation 
      8.8.1 Company Overview 
      8.8.2 Financial Overview 
      8.8.3 Product Portfolio 
      8.8.4 Business Strategies 
      8.8.5 Strategic Alliance 
      8.8.6 Recent Developments 
8.9 QIAGEN 
      8.9.1 Company Overview 
      8.9.2 Financial Overview 
      8.9.3 Product Portfolio 
      8.9.4 Business Strategies 
      8.9.5 Recent Developments 
8.10 Roche Holding AG 
      8.10.1 Company Overview 
      8.10.2 Financial Overview 
      8.10.3 Product Portfolio 
      8.10.4 Business Strategies 
      8.10.5 Recent Development 
8.11 Sigma-Aldrich Corporation 
      8.11.1 Company Overview 
      8.11.2 Financial Overview 
      8.11.3 Product Portfolio 
      8.11.4 Business Strategies 
      8.11.5 Recent Developments 
8.12 SignaGen Laboratories 
      8.12.1 Company Overview 
      8.12.2 Financial Overview 
      8.12.3 Product Portfolio 
      8.12.4 Recent Developments 
8.13 Thermo Fisher Scientific, Inc. 
      8.13.1 Company Overview 
      8.13.2 Financial Overview 
      8.13.3 Product Portfolio 
      8.13.4 Business Strategies 
      8.13.5 Recent Developments

List of Figures 

FIG. 1 Transfection Technology: Market Segmentation
FIG. 2 Global Transfection Technology Market, by Methods, 2012 (USD Million)
FIG. 3 Comparative Analysis: Global Transfection Technology Market, by Geography, 2012 and 2019 (Value %)
FIG. 4 Porter’s Five Forces Analysis: Global Transfection Technology Market
FIG. 5 Market Attractiveness Analysis: Global Transfection Technology Market, by Geography
FIG. 6 Market Share Analysis: Transfection Technology Market, 2012 (Value %)
FIG. 7 Global Lipid Mediated Transfection Market Revenue, 2011 – 2019 (USD Million)
FIG. 8 Global Calcium Phosphate Market Revenue, 2011 – 2019 (USD Million)
FIG. 9 Global Cationic Polymer Market Revenue, 2011 – 2019 (USD Million)
FIG. 10 Global DEAE-dextran Market Revenue, 2011 – 2019 (USD Million)
FIG. 11 Global Activated Dendrimers Market Revenue, 2011 – 2019 (USD Million)
FIG. 12 Global Magnetic Beads Transfection Market Revenue, 2011 – 2019 (USD Million)
FIG. 13 Global Magnetic Beads Market Revenue, 2011 – 2019 (USD Million)
FIG. 14 Global Biolistic Technology Market Revenue, 2011 – 2019 (USD Million)
FIG. 15 Global Microinjection Market Revenue, 2011 – 2019 (USD Million)
FIG. 16 Global Biolistic Technology Market Revenue, 2011 – 2019 (USD Million)
FIG. 17 Global Virus Based Method Market Revenue, 2011 – 2019 (USD Million)
FIG. 18 Global Transgenic Model Market Revenue, 2011 – 2019 (USD Million)
FIG. 19 Global Cancer Research Market Revenue, 2011 – 2019 (USD Million)
FIG. 20 Global Gene and Protein Expression Studies Market Revenue, 2011 – 2019 (USD Million)
FIG. 21 Global Cell Based Microarray for Drug Discovery and Development Market Revenue, 2011 – 2019 (USD Million)
FIG. 22 Global Biotherapeutics Market Revenue, 2011 – 2019 (USD Million)
FIG. 23 Global Electro-chemotherapy and Electro-immunotherapy Market Revenue, 2011 – 2019 (USD Million)
FIG. 24 Global Electro-chemotherapy and Electro-immunotherapy Market Revenue, 2011 – 2019 (USD Million)
FIG. 25 North America Transfection Technology Market Revenue, 2011 – 2019 (USD Million)
FIG. 26 Europe Transfection Technology Market Revenue, 2011 – 2019 (USD Million)
FIG. 27 Asia-Pacific Transfection Technology Market Revenue, 2011 – 2019 (USD Million)
FIG. 28 RoW Transfection Technology Market Revenue, 2011 – 2019 (USD Million)
FIG. 29 Annual Sales: Bio-Rad Laboratories, Inc., Life Science Segment, 2010 – 2012 (USD Million)
FIG. 30 Annual Sales: Harvard Bioscience, Inc., 2010 - 2012 (USD Million)
FIG. 31 Annual Sales: Life Technologies Corporation, 2010 – 2012 (USD Million)
FIG. 32 Annual Sales: Lonza Group Ltd., Bioscience Segment , 2010 – 2012 (USD Million)
FIG. 33 Annual Sales: Merck KGaA, Merck Millipore , 2010 – 2012 (USD Million)
FIG. 34 Annual Sales: QIAGEN, 2010 – 2012 (USD Million)
FIG. 35 Annual Sales: Roche Holding AG, 2010 – 2012 (USD Million)
FIG. 36 Annual Sales: Sigma-Aldrich Corporation, 2010 – 2012 (USD Million)
FIG. 37 Annual Sales: Thermo Fisher Scientific, 2010– 2012 (USD Million)

List of Tables

TABLE 1 List of Abbreviations
TABLE 2 Market Snapshot: Global Transfection Technology Market (2012 & 2019)
TABLE 3 Global Transfection Technology Market Revenue, by Methods, 2011 – 2019 (USD Million)
TABLE 4 Global Reagent Based Market Revenue, by Types, 2011 – 2019 (USD Million)
TABLE 5 Global Instrument Based Market Revenue, by Types, 2011 – 2019 (USD Million)
TABLE 6 Global Transfection Technology Market Revenue, by Applications, 2011 – 2019 (USD Million)
TABLE 7 Global Bio-medical Research Market Revenue, by Types, 2011 – 2019(USD)
TABLE 8 Drug Delivery Methods with their Carriers/Factors
TABLE 9 Global Therapeutics Delivery Market Revenue, by Types, 2011 – 2019 (USD Million)
TABLE 10 Global Transfection Technology Market Revenue, by Geography, 2011 – 2019 (USD Million)

 

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Free Market Analysis


Transfection is a process that involves production of genetically modified cells with the delivery of foreign nucleic acid (DNA or RNA) into the cell. There are two types of transfection technologies that include stable and transient. While stable transfection is permanent and the genes are continually expressed even after the host cell replicates, transient transfected genes are expressed for a limited period of time and are not integrated into the host genome. Increasing prevalence of cancer and growing obese population drives the global transfection technology market. In addition, initiatives taken by various government organizations also further accentuates the growth of this market. The global transfection technology market was valued at USD 386.4 million in 2012 and is expected to grow at a CAGR of 9.7% from 2013 to 2019, to reach an estimated value of USD 768.2 million by 2019.

Transfection technologymarket is segmented mainly by types of method and application. The method segment of the market is classified as reagent-based method, instrument-based method and virus-based method. The reagent-based method is further segmented as lipid mediated transfection (Lipofection), calcium phosphate, cationic polymers, DEAE-dextran, activated dendrimers and magnetic beads. Reagent based transfection technology market is experiencing significant growth owing to cost effectiveness and less complicated methods involved during transfection. Likewise, instrument-based method includes electroporation, biolistic technology, microinjection and laserfection.Instrument-based methods are less time consuming and accurate;these advantages drive the growth of this segment.

Transfection technology application market is further segmented as biomedical research, therapeutic delivery and protein production. Rising prevalence of various cancers (prostate, breast and lung), cardiovascular diseases (arrhythmias, ischemic heart disease) and growing mass protein production further accentuates the global transfection technology market. Transfection technologies have also gained widespread popularity because manufacturers are constantly coming up with new and innovative instruments that are easy to use and less complicated.It was also observed that companies who were involved in this market collaborated with the local partners to enter emerging markets of Asia and Africa. For instance, Life Technologies Corporation acquired KDR Biotech Co., Ltd., a South Korea-based distributor of reagents, in April 2013. This acquisition would further enhance Life Technologies Corporation’s revenue in the South Korean biotechnology market. Increasing prevalence of infectious diseases (H1N1, H1N5) also accentuates the demand for global transfection technology market. However, cytotoxic effects, technological complications associated with instrument-based and virus-based methods might restrict the demand of the global transfection technology market to a certain level.

North America contributed the largest share, i.e.over 45%, in 2012 of the global transfection technology market. Increasing awareness about transfection applications and various government initiativesare the major factorsdriving the growth of transfection technology market in North America.For instance, in February 2012, National Cancer Institute (NCI) signed a research agreement with Polypus Transfection S.A., a France-based, privately-held company. This agreement includes Polyethylenimine (PEI) reagent from Polypus Transfection S.A that will be utilized by the National Cancer Institute for in-vitro transfection exploration to produce transfected proteins, viruses and antibodies.Europe contributed the second largest share of the total market in 2012.Utilization of nanomedicine in diagnostics, targeted drug delivery, clinical trials and drug development studies is on the peak in Europe. Transfection technologies and reagents are combined with nanoparticles for better efficacy in the above mentioned studies. For instance, the European Commission published in 2011 that it had funded around 200 projects which include utilization of nanomedicine in research and development under sixth and seventh framework program.The Asia-Pacific region is expected to witness the fastest growth (CAGR – more than 10%)due to increasing prevalence of infectious diseases and utilization of biopharmaceuticals for drug discovery and development.

In terms of key players, the global transfection technologymarket is highly fragmented that comprises of Life Technologies Corporation, Lonza Group Ltd, Mirus Bio LLC, Polypus Transfection S.A, Promega Corporation and others.

global-transfection-technologymarket-by-methods-2012

 

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