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Cholestasis Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2016 - 2024

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Cholestasis is a condition (not a disease) where bile cannot flow from the liver to the duodenum. The two basic distinctions are an obstructive type of cholestasis where there is a mechanical blockage in the duct system that can occur from agallstone or malignancy, and metabolic types of cholestasis which are disturbances in bile formation that can occur because of genetic defects or acquired as a side effect of many medications. Based on the defect location, cholestasis can be segmented as extrahepatic cholestasis and intrahepatic cholestasis.

Cholestasis market: Symptoms

Itchiness is the primary symptom of cholestasis and is thought to be due to interactions of serum bile acids with opioidergic nerves. In fact, the opioid antagonist naltrexone is used to treat itchiness due to cholestasis. Although jaundice is an uncommon occurrence in intrahepatic (metabolic) cholestasis, but is common in obstructive cholestasis. Pale stool and dark urine are the other symptoms of obstructive cholestasis.

Cholestasis market: Causes

Bile duct tumors, pancreatitis, stones in the common bile duct, pseudocyst or pancreatic tumor, pancreatic cysts and primary sclerosing cholangitis are some of the major causes for extrahepatic cholestasis.Intrahepatic cholestasis is usually caused by hepatitis or by medications that can produce symptoms resemblinghepatitis. Intrahepatic cholestasis is also caused due to amyloidosis, bacterial abscess in the liver, lymphoma, alcoholic liver disease, pregnancy, primary sclerosing cholangitis, tuberculosis (TB), viral hepatitis and sarcoidosis. Sometimes, certain medications also result in cholestasis that include anabolic steroids, tolbutamide, prochlorperazine, estradio, terbinafine, imipramine, chlorpromazine, birth control pills and cimetidine. Cholestasis occurs in about one out of thousand pregnancies but is more common in Swedish and Chilean ethnic groups.

Cholestasis market: Diagnosis

Cholestasis can be diagnosed through CT scan, MRI scan, ultrasound and endoscopic retrograde cholangiopancreatography. Blood test will also enable physicians to determine the volume of bilirubin, and alkaline phosphatase and hence will be able to diagnose cholestasis. Cholestasis often do not respond to medical therapy, however, ursodeoxycholic acid has proven its success in increasing the secretion of bile in children to cure the disease. Liver transplantation is also performed to treat cholestasis. The market for cholestasis will grow owing to rising incidences of various diseases such as cancer, TB and lymphoma. The World Health Organization (WHO) has estimated that approximately 1.5 million people died of 9.6 million people who suffered from tuberculosis (TB) worldwide in 2014. Similarly, changing lifestyle has altered dietary pattern that will also propel the growth of this market. The major players of the market include Eli Lily and Company, Abbott Laboratories, Asklepion Pharmaceuticals, LLC and Palmetto Health among other significant players.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

The study is a source of reliable data on:

  • Market segments and sub-segments
  • Market trends and dynamics
  • Supply and demand
  • Market size
  • Current trends/opportunities/challenges
  • Competitive landscape
  • Technological breakthroughs
  • Value chain and stakeholder analysis

The regional analysis covers:

  • North America (U.S. and Canada)
  • Latin America (Mexico, Brazil, Peru, Chile, and others)
  • Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, and Luxembourg)
  • Eastern Europe (Poland and Russia)
  • Asia Pacific (China, India, Japan, ASEAN, Australia, and New Zealand)
  • Middle East and Africa (GCC, Southern Africa, and North Africa)

The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.

A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.

Highlights of the report:

  • A complete backdrop analysis, which includes an assessment of the parent market
  • Important changes in market dynamics
  • Market segmentation up to the second or third level
  • Historical, current, and projected size of the market from the standpoint of both value and volume
  • Reporting and evaluation of recent industry developments
  • Market shares and strategies of key players
  • Emerging niche segments and regional markets
  • An objective assessment of the trajectory of the market
  • Recommendations to companies for strengthening their foothold in the market

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